منابع مشابه
Current and Future Anti-Influenza Virus Drugs
In 2009, we have been experiencing a new pandemic of novel influenza virus type A (H1N1) infection. The human beings still face the threat of highly pathogenic avian influenza A (H5N1) virus. Many patients with influenza virus infection have died due to severe complications even though receiving intensive care. This suggests the need for new treatment strategies of severe influenza-associated c...
متن کاملreview of current anti-obesity drugs in obese adults
background: obesity was a dangerous chronic disease. physicians recommended drug therapy just in a few of obese patients in spite of many health risks. weight control can be improved comorbidities of obesity like hyperlipedemia, hyperinsulinoma, acanthosis nigricans and hypertension. materials and methods: this article reviewed the available original and review literatures which had been publi...
متن کامل[Cycloxygenase-2 inhibitors nonsteroid anti-inflammatory drugs: current issues.].
BACKGROUND AND OBJECTIVES Due to the high incidence of NSAID-related side-effects, the discovery of two cycloxygenase isoforms, classified as: COX-1 or constitutive and COX-2 or inductive, has formulated the paradigm that NSAIDs anti-inflammatory properties would be mediated by COX-2 inhibition, and side-effects, by COX-1 blockade. However, COX-2 has been constitutively detected in normal tissu...
متن کاملRisk-Benefit Profile of Novel Anti-diabetic Drugs: Current Perspectives
We are facing a paradigm shift in the era of antidiabetics, because agents marketed after 2008 (i.e., after the rosiglitazone saga) are not only required to reduce levels of HbA1, but also to demonstrate beneficial or at least neutral effect with regard to cardiovascular (CV) outcomes (Figure 1). This is of paramount relevance, considering that the risk of developing CV disease is two-fold high...
متن کاملCOX-2 selective nonsteroidal anti-inflammatory drugs: current status.
Since, their introduction, COX (cyclooxygenase enzyme)-2 specific inhibitors have become a rapidly growing segment of the prescription drug market. Researchers have recently focused on the potentially lethal side effects associated with their. FDA has banned the use of nimesulide (hepatotoxic) in pediatric patients and rofecoxib (cardiovascular complications) in both adults and children. COX-2 ...
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ژورنال
عنوان ژورنال: Indian Journal of Nephrology
سال: 2020
ISSN: 0971-4065
DOI: 10.4103/ijn.ijn_164_20